The Article covers some of the road blocks, there seem to be many, to heart repair using stem cells.
Not only do hearts recover poorly after injury, the prevalence of and morbidity from heart damage is high. Not surprisingly, cardiac regeneration is seen as among the most important applications of stem cell research. But although cell replacement therapy, or the successful engraftment of stem cells, works for bone marrow transplantation, this kind of cell therapy will be much more difficult in solid organs, at least according to results, presented at the June 2007 meeting of the ISSCR. Indeed, not only does heart tissue fail to promote integration of transplanted cardiomyocytes, it may even provide a hostile environment.
Tags: CHD, ESC, Heart Damage
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